Newsletter Section	Paper Name	Objective	Method	Subjects	Results
Protein 101 A Study in Protein Recommendations The Great Protein Fiasco: Historical Perspective on a Nutrition Mistake Protein and the Elderly	Protein and amino acid requirements in human nutrition WHO technical report series. #935. Impact factor : - Citations : 330	Conceptual framework for estimating protein and amino acid requirements Statistical concepts and procedures involved in deriving recommendations for protein and amino acid requirements General methods used for determining protein and amino acid requirements Protein–energy interactions Protein quality evaluation Protein requirements of adults, including older people, andwomen during pregnancy and lactation Amino acid requirements of adults Protein and amino acid requirements of infants and children Catch-up growth Influence of infection on protein and amino acid requirements Implications of the protein and amino acid requirements for populations in developed and developing countries Protein intake and health	NA	NA	NA
Protein 101	What is the total number of protein molecules per cell volume? A call to rethink some published value BioEssays 2013 Impact factor : 4.080 Citations : 352	Estimate the expected total number of proteins per unit of cell volume.	Mass-spectrometry	NA	We estimate a range of 2-4 million proteins per cubic micron in bacteria,yeast, and mammalian cells.
Protein 101	Position of the Academy of Nutrition and Dietetics: Vegetarian Diets Journal of the Academy of Nutrition and Dietetics Impact factor : 4.141 Citations : 459	Appropriately planned vegetarian, including vegan diets are healthful, nutritionally adequate, and may provide health benefits in the prevention and treatment of certain diseases.	NA	NA	Overall nutrition, as assessed by the Alternative HealthyEating Index, is typically better on vegetarian and vegan diets compared with omnivorous diets. While some vegetarian diets may be low in certain nutrients, such as calcium and vitaminB-12, this can be remedied by appropriate planning. Compared to non vegetarian diets, vegetarian diets can provide protection against many chronic diseases, such as heart disease,hypertension, type 2 diabetes, obesity,and some cancers.
A Study in Protein Recommendation	Meta-analysis of nitrogen balance studies for estimating protein requirements in healthy adults American Journal of Clinical Nutrition 2003 Impact factor : 6.77 Citations : 495	Analyze available nitrogen balance data to establish new recommendations for the protein required by healthy adults	Meta-analysis	Data for 235 individual subjects, each studied at ≥ 3 test protein intakes, were gathered from 19 studies.	This meta-analysis provides new recommendations for dietary reference values, i.e. an EAR (median) and RDA (97.5th percentile) for healthy adults of 105 and 132 mgN/kg/d (0.65g and 0.83g good-quality protein per kg/d), respectively
The Great Protein Fiasco: Historical Perspective on a Nutrition Mistake	The Great Protein Fiasco The Lancet Impact factor : 60.392 Citations : 311	To establish cause for malnutritional disease like kwashiorkor			Lack of nutriment in general with an energy gap rather than a protein gap is the crux of the matter of kwashiorkor in children. We still do not know, for instance, whether or not many of us are actually eating levelsof protein that are harmfully high.
Excess Protein ≠ Excess Muscle	Maximal Rates of Excretion and Synthesis of Urea in Normal and Cirrhotic Subjects Journal of Clinical Investigation Impact Factor : 11.864 Citations : 243	Effect of protein intake on maximal rates of excretion and synthesis of urea in normal and cirrhotic subject			Among 19 cirrhotic patients fed 40, 60, 80, or 100g protein daily for successive 10 day periods, the occurrences of hyperammonemia, hyperaminoacidemia, and encephalopathy at each level of protein intake were inversely related maximum rate of urea synthesis (MRUS) value
The Great Protein Fiasco: Historical Perspective on a Nutrition Mistake	Clinical effects of two different levels of protein intake on low-birth-weight infants The Journal of Pediatrics, 1969 Impact factor : 3.890 Citations : 89	A controlled clinical trial	304 infants below 2kg weight	The infants fed the higher intake had more fever, lethargy, and poor nipple feeding, but they had higher plasma protein levels and less edema than infants fed the lower intake.
Excess Protein ≠ Excess Muscle	Protein requirements and muscle mass/strength changes during intensive training in novice bodybuilders Journal of Applied Physiology, 1992 Impact factor : 1.86 Citations : 461	To assessed protein (PRO) requirements during the early stages of intensive bodybuilding training and determine whether supplemental protein enhanced muscle mass/strength gains	Randomized double-blind cross-over study	Twelve men [22.4 t 2.4 (SD) yr]	Data indicate that, during the early stages of intensive bodybuilding training, PRO needs are - 100% greater than current recommendations but that protein intake increases from 1.35 to 2.62 g per kg per day do not enhance muscle mass/strength gains, at least during the 1st month of training.
Excess Protein ≠ Excess Muscle	Protein requirements and supplementation in strength sports Nutrition Elsiver, 2004 Impact factor : - Citations : 420
Protein and the Elderly	Nutrition and sarcopenia: evidence for an interaction Proceedings of the nutrition society, 2012 Impact factor : 4.403 Citations : 92	Nutritional interventions that might influence sarcopenia, as indicated by literature reporting onsarcopeniaper seas well as dynapenia and frailty, are reviewed in relation to potentialphysiological aetiological factors.			There is insufficient evidence for any more specific nutritional advice than that contained in the general healthy lifestyle.
Protein and the Elderly	The impact of dietary protein intake on longevity and metabolic health EBioMedicine, 2019 Impact factor : 5.636 Citations : 27	To elucidate the specific restriction levels of individual AAs (amino acids) that are most effective for longevity/metabolic health in humans.			An individual may need to eat less animal-based foodto achieve MetR. For example, the Mediterranean diet or the Dietary Approaches to Stop Hypertension (DASH) diet may be useful for decreasing the consumption of animal protein, particularly red meat. However, red meat is an important dietary source of micronutrients, including vitamins, iron and zinc; therefore, an appro-priate intake is necessary to avoid malnutrition.
Cavemen Most Likely Did Not Have a High Protein Diet	Paleolithic diets: a sceptical view Nutrition Bulletin, 2000 Impact Factor : - Citations : 35	This review examines some of the archaeological evidence relating to the diets of early man and other primates, and current hunter‐gatherer societies.			The evidence related to Paleolithic diets is best interpreted as supporting the idea that diets based largely on plant foods promote health and longevity, at least under conditions of food abundance and physical activity.
Cavemen Most Likely Did Not Have a High Protein Diet	Twenty questions on atherosclerosis Proceedings (Baylor University. Medical Center Impact factor : - Citations : 14	Questions answered by an MD on atherosclerosis	QA	NA	NA